Functional Flexibility of the FimH Adhesin: Insights from a Random Mutant Library
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چکیده
منابع مشابه
Functional flexibility of the FimH adhesin: insights from a random mutant library.
Type 1 fimbriae are surface organelles of Escherichia coli which mediate D-mannose-sensitive binding to different host surfaces. This binding is conferred by the minor fimbrial component FimH. Naturally occurring variants of the FimH protein have been selected in nature for their ability to recognize specific receptor targets. In particular, variants that bind strongly to terminally exposed mon...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2000
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.68.5.2638-2646.2000